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Regulatory T cells in embryo implantation and the immune response to pregnancy

At implantation, the embryo expresses paternally derived alloantigens and evokes inflammation that can threaten reproductive success. To ensure a robust placenta and sustainable pregnancy, an active state of maternal immune tolerance mediated by CD4(+) regulatory T cells (Tregs) is essential. Tregs...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Robertson, Sarah A., Care, Alison S., Moldenhauer, Lachlan M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6159994/
https://ncbi.nlm.nih.gov/pubmed/30272581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI122182
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