No recovery of replication-competent HIV-1 from human liver macrophages

Long-lived HIV-1 reservoirs that persist despite antiretroviral therapy (ART) are a major impediment to a cure for HIV-1. We examined whether human liver macrophages (LMs), the largest tissue macrophage population, comprise an HIV-1 reservoir. We purified LMs from liver explants and included treatme...

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Publicado en:J Clin Invest
Main Authors: Kandathil, Abraham J., Sugawara, Sho, Goyal, Ashish, Durand, Christine M., Quinn, Jeffrey, Sachithanandham, Jaiprasath, Cameron, Andrew M., Bailey, Justin R., Perelson, Alan S., Balagopal, Ashwin
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 2018
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6159970/
https://ncbi.nlm.nih.gov/pubmed/30198905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI121678
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