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Optimal Cut-Off Value for Locus Coeruleus-to-Pons Intensity Ratio as Clinical Biomarker for Alzheimer’s Disease: A Pilot Study

BACKGROUND: Studies using neuromelanin-sensitive-MRI have established the locus coeruleus (LC)-to-pons intensity ratio as a biomarker for diagnosis of Parkinson’s and Alzheimer’s diseases. More detailed analysis is needed for exploiting the highest clinical potential of this technique. OBJECTIVE: Th...

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Detalhes bibliográficos
Publicado no:J Alzheimers Dis Rep
Main Authors: Dordevic, Milos, Müller-Fotti, Alessa, Müller, Patrick, Schmicker, Marlen, Kaufmann, Jörn, Müller, Notger G.
Formato: Artigo
Idioma:Inglês
Publicado em: IOS Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6159723/
https://ncbi.nlm.nih.gov/pubmed/30480235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/ADR-170021
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