Macrophage migration inhibitory factor enhances Pseudomonas aeruginosa biofilm formation, potentially contributing to cystic fibrosis pathogenesis

Macrophage migration inhibitory factor (MIF) is a key proinflammatory mediator that we have previously shown to be associated with an aggressive clinical phenotype in cystic fibrosis. It possesses unique tautomerase enzymatic activity. However, to date, no human-derived substrate has been identified...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:FASEB J
Egile Nagusiak: Tynan, Aisling, Mawhinney, Leona, Armstrong, Michelle E., O’Reilly, Ciaran, Kennedy, Sarah, Caraher, Emma, Jülicher, Karen, O’Dwyer, David, Maher, Lewena, Schaffer, Kirsten, Fabre, Aurélie, McKone, Edward F., Leng, Lin, Bucala, Richard, Bernhagen, Jürgen, Cooke, Gordon, Donnelly, Seamas C.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Federation of American Societies for Experimental Biology 2017
Gaiak:
Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6159708/
https://ncbi.nlm.nih.gov/pubmed/28768722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201700463R
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