Macrophage migration inhibitory factor enhances Pseudomonas aeruginosa biofilm formation, potentially contributing to cystic fibrosis pathogenesis

Macrophage migration inhibitory factor (MIF) is a key proinflammatory mediator that we have previously shown to be associated with an aggressive clinical phenotype in cystic fibrosis. It possesses unique tautomerase enzymatic activity. However, to date, no human-derived substrate has been identified...

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Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:FASEB J
Κύριοι συγγραφείς: Tynan, Aisling, Mawhinney, Leona, Armstrong, Michelle E., O’Reilly, Ciaran, Kennedy, Sarah, Caraher, Emma, Jülicher, Karen, O’Dwyer, David, Maher, Lewena, Schaffer, Kirsten, Fabre, Aurélie, McKone, Edward F., Leng, Lin, Bucala, Richard, Bernhagen, Jürgen, Cooke, Gordon, Donnelly, Seamas C.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Federation of American Societies for Experimental Biology 2017
Θέματα:
Research
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6159708/
https://ncbi.nlm.nih.gov/pubmed/28768722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201700463R
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