Macrophage migration inhibitory factor enhances Pseudomonas aeruginosa biofilm formation, potentially contributing to cystic fibrosis pathogenesis

Macrophage migration inhibitory factor (MIF) is a key proinflammatory mediator that we have previously shown to be associated with an aggressive clinical phenotype in cystic fibrosis. It possesses unique tautomerase enzymatic activity. However, to date, no human-derived substrate has been identified...

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Dades bibliogràfiques
Publicat a:FASEB J
Autors principals: Tynan, Aisling, Mawhinney, Leona, Armstrong, Michelle E., O’Reilly, Ciaran, Kennedy, Sarah, Caraher, Emma, Jülicher, Karen, O’Dwyer, David, Maher, Lewena, Schaffer, Kirsten, Fabre, Aurélie, McKone, Edward F., Leng, Lin, Bucala, Richard, Bernhagen, Jürgen, Cooke, Gordon, Donnelly, Seamas C.
Format: Artigo
Idioma:Inglês
Publicat: Federation of American Societies for Experimental Biology 2017
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6159708/
https://ncbi.nlm.nih.gov/pubmed/28768722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201700463R
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