Methylation Profiling RIN3 and MEF2C Identifies Epigenetic Marks Associated with Sporadic Early Onset Alzheimer’s Disease

A number of genetic loci associate with early onset Alzheimer’s disease (EOAD); however, the drivers of this disease remains enigmatic. Genome wide association and in vivo modeling have shown that loss-of-function, e.g., ABCA7, reduced levels of SIRT1 and MEFF2C, or increased levels of PTK2β confer...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Alzheimers Dis Rep
Main Authors: Boden, Kirsty A., Barber, Imelda S., Clement, Naomi, Patel, Tulsi, Guetta-Baranes, Tamar, Brookes, Keeley J., Chappell, Sally, Craigon, Jim, Chapman, Natalie H., Morgan, Kevin, Seymour, Graham B., Bottley, Andrew
Formato: Artigo
Idioma:Inglês
Publicado em: IOS Press 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6159661/
https://ncbi.nlm.nih.gov/pubmed/30480232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/ADR-170015
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados