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Evaluation of an OV-16 IgG4 Enzyme-Linked Immunosorbent Assay in Humans and Its Application to Determine the Dynamics of Antibody Responses in a Non-Human Primate Model of Onchocerca volvulus Infection

Onchocerciasis is a neglected parasitic disease targeted for elimination. Current World Health Organization guidelines for elimination include monitoring antibody responses to the recombinant Onchocerca volvulus antigen OV-16 in children to demonstrate the absence of transmission. We report the perf...

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Veröffentlicht in:Am J Trop Med Hyg
Hauptverfasser: Cama, Vitaliano A., McDonald, Circe, Arcury-Quandt, Alice, Eberhard, Mark, Jenks, M. Harley, Smith, Jared, Feleke, Sindew M., Abanyie, Francisca, Thomson, Lakwo, Wiegand, Ryan E., Cantey, Paul T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society of Tropical Medicine and Hygiene 2018
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6159584/
https://ncbi.nlm.nih.gov/pubmed/30062989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4269/ajtmh.18-0132
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