Mesenchymal stem cells recruited by castration-induced inflammation activation accelerate prostate cancer hormone resistance via chemokine ligand 5 secretion

BACKGROUND: Androgen deprivation (AD) as the first-line treatment for advanced prostate cancer (PCa) is insufficient for a long-term effect. Castration resistance remains the greatest obstacle in PCa clinical therapy. Mesenchymal stem cells (MSCs) can migrate into PCa tissues contributing to tumor p...

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Vydáno v:Stem Cell Res Ther
Hlavní autoři: Yu, Yang, Zhang, Qingyun, Ma, Chengzhong, Yang, Xue, Lin, Rui, Zhang, Hongxiang, Liu, Yan, Han, Zhipeng, Cheng, Jiwen
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2018
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6158918/
https://ncbi.nlm.nih.gov/pubmed/30257726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-018-0989-8
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