Restriction-deficient mutants and marker-less genomic modification for metabolic engineering of the solvent producer Clostridium saccharobutylicum

BACKGROUND: Clostridium saccharobutylicum NCP 262 is a solventogenic bacterium that has been used for the industrial production of acetone, butanol, and ethanol. The lack of a genetic manipulation system for C. saccharobutylicum currently limits (i) the use of metabolic pathway engineering to improv...

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Bibliographic Details
Published in:Biotechnol Biofuels
Main Authors: Huang, Ching-Ning, Liebl, Wolfgang, Ehrenreich, Armin
Format: Artigo
Language:Inglês
Published: BioMed Central 2018
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6158908/
https://ncbi.nlm.nih.gov/pubmed/30275904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13068-018-1260-3
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