MSC-derived exosomes ameliorate erectile dysfunction by alleviation of corpus cavernosum smooth muscle apoptosis in a rat model of cavernous nerve injury

BACKGROUND: This study investigated the therapeutic effects of MSC-derived exosomes (MSC-Exos) on erectile function in a rat model of cavernous nerve injury (CNI). METHODS: MSCs were isolated from rat bone marrow and exosomes were isolated from the supernatants by ultracentrifugation. The tissue exp...

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Enregistré dans:
Détails bibliographiques
Publié dans:Stem Cell Res Ther
Auteurs principaux: Ouyang, Xi, Han, Xiaoyan, Chen, Zehong, Fang, Jiafeng, Huang, Xuna, Wei, Hongbo
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2018
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6158845/
https://ncbi.nlm.nih.gov/pubmed/30257719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-018-1003-1
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