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Thrombopoietin could protect cerebral tissue against ischemia-reperfusion injury by suppressing NF-κB and MMP-9 expression in rats

Objective: To determine the neuroprotective effects and underpinning mechanisms of thrombopoietin (TPO), Matrix Metalloproteinase-9(MMP-9) and Nuclear Factor-κB (NF-κB) after focal cerebral ischemia-reperfusion in rats. Methods: Male rats underwent 2 hours of right middle cerebral artery occlusion (...

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Detalhes bibliográficos
Publicado no:Int J Med Sci
Main Authors: Wu, Wenjuan, Zhong, Wei, Lang, Bing, Hu, Zhiping, He, Jialin, Tang, Xiangqi
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6158660/
https://ncbi.nlm.nih.gov/pubmed/30275761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijms.27543
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