CDKN2A as transcriptomic marker for muscle-invasive bladder cancer risk stratification and therapy decision-making

Deletions of the cell cycle control gene CDKN2A are described as progression markers of non-muscle invasive bladder cancer and to be associated with fibroblast growth factor 3 (FGFR3) mutations. The prognostic role of CDKN2A RNA expression in muscle invasive bladder cancer (MIBC) is under discussion...

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Vydáno v:Sci Rep
Hlavní autoři: Worst, Thomas S., Weis, Cleo-Aron, Stöhr, Robert, Bertz, Simone, Eckstein, Markus, Otto, Wolfgang, Breyer, Johannes, Hartmann, Arndt, Bolenz, Christian, Wirtz, Ralph M., Erben, Philipp
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6158275/
https://ncbi.nlm.nih.gov/pubmed/30258198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-32569-x
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