Genetic risk for schizophrenia and autism, social impairment and developmental pathways to psychosis

While psychotic experiences (PEs) are assumed to represent psychosis liability, general population studies have not been able to establish significant associations between polygenic risk scores (PRS) and PEs. Previous work suggests that PEs may only represent significant risk when accompanied by soc...

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Vydáno v:Transl Psychiatry
Hlavní autoři: Velthorst, Eva, Froudist-Walsh, Sean, Stahl, Eli, Ruderfer, Douglas, Ivanov, Ilyan, Buxbaum, Joseph, Banaschewski, Tobias, Bokde, Arun L. W., Dipl-Psych, Uli Bromberg, Büchel, Christian, Quinlan, Erin Burke, Desrivières, Sylvane, Flor, Herta, Frouin, Vincent, Garavan, Hugh, Gowland, Penny, Heinz, Andreas, Ittermann, Bernd, Martinot, Marie-Laure Paillère, Artiges, Eric, Nees, Frauke, Orfanos, Dimitri Papadopoulos, Paus, Tomáš, Poustka, Luise, Hohmann, Sarah, Fröhner, Juliane H., Smolka, Michael N., Walter, Henrik, Whelan, Robert, Schumann, Gunter, Reichenberg, Abraham
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6158250/
https://ncbi.nlm.nih.gov/pubmed/30258131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41398-018-0229-0
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