UBL3 modification influences protein sorting to small extracellular vesicles

Exosomes, a type of small extracellular vesicles (sEVs), derived from multivesicular bodies (MVBs), mediate cell-to-cell communication by transporting proteins, mRNAs, and miRNAs. However, the molecular mechanism by which proteins are sorted to sEVs is not fully understood. Here, we report that ubiq...

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Publié dans:Nat Commun
Auteurs principaux: Ageta, Hiroshi, Ageta-Ishihara, Natsumi, Hitachi, Keisuke, Karayel, Ozge, Onouchi, Takanori, Yamaguchi, Hisateru, Kahyo, Tomoaki, Hatanaka, Ken, Ikegami, Koji, Yoshioka, Yusuke, Nakamura, Kenji, Kosaka, Nobuyoshi, Nakatani, Masashi, Uezumi, Akiyoshi, Ide, Tomihiko, Tsutsumi, Yutaka, Sugimura, Haruhiko, Kinoshita, Makoto, Ochiya, Takahiro, Mann, Matthias, Setou, Mitsutoshi, Tsuchida, Kunihiro
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2018
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6158211/
https://ncbi.nlm.nih.gov/pubmed/30258067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06197-y
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