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Multi-omics integrative analysis with genome-scale metabolic model simulation reveals global cellular adaptation of Aspergillus niger under industrial enzyme production condition

Oxygen limitation is regarded as a useful strategy to improve enzyme production by mycelial fungus like Aspergillus niger. However, the intracellular metabolic response of A. niger to oxygen limitation is still obscure. To address this, the metabolism of A. niger was studied using multi-omics integr...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Lu, Hongzhong, Cao, Weiqiang, Liu, Xiaoyun, Sui, Yufei, Ouyang, Liming, Xia, Jianye, Huang, Mingzhi, Zhuang, Yingping, Zhang, Siliang, Noorman, Henk, Chu, Ju
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6158188/
https://ncbi.nlm.nih.gov/pubmed/30258063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-32341-1
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