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The effect of cellular context on miR-155-mediated gene regulation in four major immune cell types

Numerous microRNAs and their target mRNAs are co-expressed across diverse cell types. However, it is unknown whether they are regulated in a cellular context-independent or -dependent manner. Here, we explored transcriptome-wide targeting and gene regulation by miR-155, whose activation-induced expr...

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Publicat a:Nat Immunol
Autors principals: Hsin, Jing-Ping, Lu, Yuheng, Loeb, Gabriel B., Leslie, Christina S., Rudensky, Alexander Y.
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6158091/
https://ncbi.nlm.nih.gov/pubmed/30224821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41590-018-0208-x
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