Single Locked Nucleic Acid-Enhanced Nanopore Genetic Discrimination of Pathogenic Serotypes and Cancer Driver Mutations

Accurate and rapid detection of single-nucleotide polymorphism (SNP) in pathogenic mutants is crucial for many fields such as food safety regulation and disease diagnostics. Current detection methods involve laborious sample preparations and expensive characterizations. Here, we investigated a singl...

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Detalhes bibliográficos
Publicado no:ACS Nano
Main Authors: Tian, Kai, Chen, Xiaowei, Luan, Binquan, Singh, Prashant, Yang, Zhiyu, Gates, Kent S., Lin, Mengshi, Mustapha, Azlin, Gu, Li-Qun
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6157732/
https://ncbi.nlm.nih.gov/pubmed/29664612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsnano.8b01198
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