Protocol for the insight study: a randomised controlled trial of single-dose tocilizumab in patients with depression and low-grade inflammation

INTRODUCTION: Observational studies indicate a potentially causal role for interleukin 6 (IL-6), a proinflammatory cytokine, in pathogenesis of depression, but interventional studies based on patients with depression have not been conducted. Tocilizumab, anti-inflammatory drug, is a humanised monocl...

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Bibliografiske detaljer
Udgivet i:BMJ Open
Main Authors: Khandaker, Golam M, Oltean, Bianca P, Kaser, Muzaffer, Dibben, Claire R M, Ramana, Rajini, Jadon, Deepak R, Dantzer, Robert, Coles, Alasdair J, Lewis, Glyn, Jones, Peter B
Format: Artigo
Sprog:Inglês
Udgivet: BMJ Publishing Group 2018
Fag:
Mental Health
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6157523/
https://ncbi.nlm.nih.gov/pubmed/30244217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjopen-2018-025333
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