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The Myogenic Regulatory Circuit That Controls Cardiac/Slow Twitch Troponin C Gene Transcription in Skeletal Muscle Involves E-box, MEF-2, and MEF-3 Motifs

We have characterized the specific DNA regulatory elements responsible for the function of the human cardiac troponin C gene (cTnC) muscle-specific enhancer in myogenic cells. We used functional transient transfection assays with deletional and site-specific mutagenesis to evaluate the role of the c...

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Bibliografische gegevens
Gepubliceerd in:Gene Expr
Hoofdauteurs: Christensen, Thorkil H., Kedes, Larry
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Cognizant Communication Corporation 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6157365/
https://ncbi.nlm.nih.gov/pubmed/10794526
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