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An adaptive gene-level association test for pedigree data
BACKGROUND: We propose a gene-level association test that accounts for individual relatedness and population structures in pedigree data in the framework of linear mixed models (LMMs). Our method data-adaptively combines the results across a class of score-based tests, only requiring fitting a singl...
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| Publicado no: | BMC Genet |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6157189/ https://ncbi.nlm.nih.gov/pubmed/30255770 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12863-018-0639-2 |
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