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Reliability of genomic predictions of complex human phenotypes

Genome-wide association studies have helped us identify a wealth of genetic variants associated with complex human phenotypes. Because most variants explain a small portion of the total phenotypic variation, however, marker-based studies remain limited in their ability to predict such phenotypes. He...

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Detalhes bibliográficos
Publicado no:BMC Proc
Main Authors: Porto, Arthur, Peralta, Juan M., Blackburn, Nicholas B., Blangero, John
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6157117/
https://ncbi.nlm.nih.gov/pubmed/30275897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12919-018-0138-5
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