VarExp: estimating variance explained by genome-wide GxE summary statistics

SUMMARY: Many genome-wide association studies and genome-wide screening for gene–environment (GxE) interactions have been performed to elucidate the underlying mechanisms of human traits and diseases. When the analyzed outcome is quantitative, the overall contribution of identified genetic variants...

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Pubblicato in:Bioinformatics
Autori principali: Laville, Vincent, Bentley, Amy R, Privé, Florian, Zhu, Xiaofeng, Gauderman, Jim, Winkler, Thomas W, Province, Mike, Rao, D C, Aschard, Hugues
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6157079/
https://ncbi.nlm.nih.gov/pubmed/29726908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bty379
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