Hematopoietic protease nexin-1 protects against lung injury by preventing thrombin signaling in mice

Coagulation and fibrinolytic system deregulation has been implicated in the development of idiopathic pulmonary fibrosis, a devastating form of interstitial lung disease. We used intratracheal instillation of bleomycin to induce pulmonary fibrosis in mice and analyzed the role of serine protease inh...

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Detalhes bibliográficos
Publicado no:Blood Adv
Main Authors: François, Deborah, Arocas, Véronique, Venisse, Laurence, Aymonnier, Karen, Idir, Leila, Martos, Raphael, Gazit, Salome, Couty, Ludovic, Jandrot-Perrus, Martine, Camerer, Eric, Boulaftali, Yacine, Bouton, Marie-Christine
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2018
Assuntos:
Vascular Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6156894/
https://ncbi.nlm.nih.gov/pubmed/30254103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2018018283
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