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CMTM6 overexpression is associated with molecular and clinical characteristics of malignancy and predicts poor prognosis in gliomas

CMTM6, a previously uncharacterized protein, was identified as a critical regulator of PD-L1, which is reported as an immune checkpoint inhibitor, to modulate the T cell activities both in vitro and in vivo of other tumors. However, the role of CMTM6 has so far remained unclear in glioma. To investi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:EBioMedicine
Hauptverfasser: Guan, Xiudong, Zhang, Chuanbao, Zhao, Jingyan, Sun, George, Song, Qingkun, Jia, Wang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6156716/
https://ncbi.nlm.nih.gov/pubmed/30131308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2018.08.012
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