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High-resolution repertoire analysis reveals a major bystander activation of Tfh and Tfr cells

T follicular helper (Tfh) and regulatory (Tfr) cells are terminally differentiated cells found in germinal centers (GCs), specialized secondary lymphoid organ structures dedicated to antibody production. As such, follicular T (Tfol) cells are supposed to be specific for immunizing antigens, which ha...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Ritvo, Paul-Gydeon, Saadawi, Ahmed, Barennes, Pierre, Quiniou, Valentin, Chaara, Wahiba, El Soufi, Karim, Bonnet, Benjamin, Six, Adrien, Shugay, Mikhail, Mariotti-Ferrandiz, Encarnita, Klatzmann, David
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6156623/
https://ncbi.nlm.nih.gov/pubmed/30158170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1808594115
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