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Modeling of mesenchymal hybrid epithelial state and phenotypic transitions in EMT and MET processes of cancer cells

Based on the transcriptional regulatory mechanisms between microRNA-200 and transcription factor ZEB in an individual cancer cell, a minimal dynamic model is proposed to study the epithelial-mesenchymal transition (EMT) and mesenchymal-epithelial transition (MET) processes of cancer cells. It is sho...

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Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: He, Peng, Qiu, Kang, Jia, Ya
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6156327/
https://ncbi.nlm.nih.gov/pubmed/30254295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-32737-z
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