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Biology, role and therapeutic potential of circulating histones in acute inflammatory disorders

Histones are positively charged nuclear proteins that facilitate packaging of DNA into nucleosomes common to all eukaryotic cells. Upon cell injury or cell signalling processes, histones are released passively through cell necrosis or actively from immune cells as part of extracellular traps. Extrac...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Szatmary, Peter, Huang, Wei, Criddle, David, Tepikin, Alexei, Sutton, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6156248/
https://ncbi.nlm.nih.gov/pubmed/30085397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13797
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