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GADD45a Regulates Olaquindox-Induced DNA Damage and S-Phase Arrest in Human Hepatoma G2 Cells via JNK/p38 Pathways

Olaquindox, a quinoxaline 1,4-dioxide derivative, is widely used as a feed additive in many countries. The potential genotoxicity of olaquindox, hence, is of concern. However, the proper mechanism of toxicity was unclear. The aim of the present study was to investigate the effect of growth arrest an...

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Publicat a:Molecules
Autors principals: Li, Daowen, Dai, Chongshan, Yang, Xiayun, Li, Bin, Xiao, Xilong, Tang, Shusheng
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6155949/
https://ncbi.nlm.nih.gov/pubmed/28098804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules22010124
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