Reaction of 3-Amino-1,2,4-Triazole with Diethyl Phosphite and Triethyl Orthoformate: Acid-Base Properties and Antiosteoporotic Activities of the Products

The reaction of diethyl phosphite with triethyl orthoformate and a primary amine followed by hydrolysis is presented, and the reaction was suitable for the preparation of (aminomethylene)bisphosphonates. 3-Amino-1,2,4-triazole was chosen as an interesting substrate for this reaction because it posse...

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Bibliografische gegevens
Gepubliceerd in:Molecules
Hoofdauteurs: Miszczyk, Patrycja, Wieczorek, Dorota, Gałęzowska, Joanna, Dziuk, Błażej, Wietrzyk, Joanna, Chmielewska, Ewa
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2017
Onderwerpen:
Communication
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6155913/
https://ncbi.nlm.nih.gov/pubmed/28208725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules22020254
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