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Synthesis and Antitumor Activities of Chiral Dipeptide Thioureas Containing an Alpha-Aminophosphonate Moiety

Thiourea derivatives demonstrate potent cytotoxic activity against various leukemias and many tumor cell lines. In our previous study, the combination of thiourea and phosphonate has been proven as an effective strategy for developing antitumor agents. Herein, we synthesized and evaluated a series o...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Molecules
Hauptverfasser: Liu, Jingzi, Liao, Peng, Hu, Junfeng, Zhu, Hong, Wang, Yonglin, Li, Yongjun, Li, Yan, He, Bin
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6155911/
https://ncbi.nlm.nih.gov/pubmed/28212338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules22020238
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