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Biopharmaceutical Characterization and Bioavailability Study of a Tetrazole Analog of Clofibric Acid in Rat

In the current investigation, the physicochemical, biopharmaceutical and pharmacokinetic characterization of a new clofibric acid analog (Compound 1) was evaluated. Compound 1 showed affinity by lipophilic phase in 1 to 5 pH interval, indicating that this compound would be absorbed favorably in duod...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Vara-Gama, Nancy, Valladares-Méndez, Adriana, Navarrete-Vazquez, Gabriel, Estrada-Soto, Samuel, Orozco-Castellanos, Luis Manuel., Rivera-Leyva, Julio César
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6155746/
https://ncbi.nlm.nih.gov/pubmed/28216581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules22020282
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