Colonic levels of vasoactive intestinal peptide decrease during infection and exogenous VIP protects epithelial mitochondria against the negative effects of IFNγ and TNFα induced during Citrobacter rodentium infection

Citrobacter rodentium infection is a model for infection with attaching and effacing pathogens, such as enteropathogenic Escherichia coli. The vasoactive intestinal peptide (VIP) has emerged as an anti-inflammatory agent, documented to inhibit Th1 immune responses and successfully treat animal model...

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Publicat a:PLoS One
Autors principals: Maiti, Arpan K., Sharba, Sinan, Navabi, Nazanin, Lindén, Sara K.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2018
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6155558/
https://ncbi.nlm.nih.gov/pubmed/30252907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0204567
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