Extracellular matrix with defective collagen cross-linking affects the differentiation of bone cells

Fibrillar type I collagen, the predominant organic component in bone, is stabilized by lysyl oxidase (LOX)-initiated covalent intermolecular cross-linking, an important determinant of bone quality. However, the impact of collagen cross-linking on the activity of bone cells and subsequent tissue remo...

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Publicado en:PLoS One
Autores principales: Ida, Takako, Kaku, Masaru, Kitami, Megumi, Terajima, Masahiko, Rosales Rocabado, Juan Marcelo, Akiba, Yosuke, Nagasawa, Masako, Yamauchi, Mitsuo, Uoshima, Katsumi
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6155528/
https://ncbi.nlm.nih.gov/pubmed/30252876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0204306
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