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Conservation of the Keap1-Nrf2 System: An Evolutionary Journey through Stressful Space and Time
The Keap1-Nrf2 system is an evolutionarily conserved defense mechanism against oxidative and xenobiotic stress. Its regulatory mechanisms, e.g., stress-sensing mechanism, proteasome-based regulation of Nrf2 activity and selection of target genes, have been elucidated mainly in mammals. In addition,...
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| Udgivet i: | Molecules |
|---|---|
| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
MDPI
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6155405/ https://ncbi.nlm.nih.gov/pubmed/28282941 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules22030436 |
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