Rapamycin and fasting sustain autophagy response activated by ischemia/reperfusion injury and promote retinal ganglion cell survival

Autophagy, the cellular process responsible for degradation and recycling of cytoplasmic components through the autophagosomal–lysosomal pathway, is fundamental for neuronal homeostasis and its deregulation has been identified as a hallmark of neurodegeneration. Retinal hypoxic–ischemic events occur...

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Publicat a:Cell Death Dis
Autors principals: Russo, Rossella, Varano, Giuseppe Pasquale, Adornetto, Annagrazia, Nazio, Francesca, Tettamanti, Gianluca, Girardello, Rossana, Cianfanelli, Valentina, Cavaliere, Federica, Morrone, Luigi Antonio, Corasaniti, Maria Tiziana, Cecconi, Francesco, Bagetta, Giacinto, Nucci, Carlo
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6155349/
https://ncbi.nlm.nih.gov/pubmed/30250019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-1044-5
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