Rapamycin and fasting sustain autophagy response activated by ischemia/reperfusion injury and promote retinal ganglion cell survival

Autophagy, the cellular process responsible for degradation and recycling of cytoplasmic components through the autophagosomal–lysosomal pathway, is fundamental for neuronal homeostasis and its deregulation has been identified as a hallmark of neurodegeneration. Retinal hypoxic–ischemic events occur...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Russo, Rossella, Varano, Giuseppe Pasquale, Adornetto, Annagrazia, Nazio, Francesca, Tettamanti, Gianluca, Girardello, Rossana, Cianfanelli, Valentina, Cavaliere, Federica, Morrone, Luigi Antonio, Corasaniti, Maria Tiziana, Cecconi, Francesco, Bagetta, Giacinto, Nucci, Carlo
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6155349/
https://ncbi.nlm.nih.gov/pubmed/30250019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-1044-5
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