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Facial Regioselective Synthesis of Novel Bioactive Spiropyrrolidine/Pyrrolizine-Oxindole Derivatives via a Three Components Reaction as Potential Antimicrobial Agents

This article presents the synthesis of new derivatives of spirooxindole-spiropiperidinone- pyrrolidines 6a–j and spirooxindole-spiropiperidinone-pyrrolizines 8a–j, through a 1,3-dipolar cycloaddition reaction of azomethineylides generated from isatin, sarcosine, and l-proline, through a decarboxylat...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Hassaneen, Huwaida M. E., Eid, Elshimaa M., Eid, Hamid A., Farghaly, Thoraya A., Mabkhot, Yahia Nasser
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6155345/
https://ncbi.nlm.nih.gov/pubmed/28245641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules22030357
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