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Three-Component Reaction of Benzylamines, Diethyl Phosphite and Triethyl Orthoformate: Dependence of the Reaction Course on the Structural Features of the Substrates and Reaction Conditions

The reaction between benzyl amines, triethyl orthoformate, and diethyl phosphite affords either bisphosphonic (compound 1) or N-benzylaminobenzylphosphonic (compound 2) acid depending on the reaction conditions. The final output of the reaction can be manipulated by the choice of reaction conditions...

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Bibliographic Details
Published in:Molecules
Main Authors: Miszczyk, Patrycja, Turowska-Tyrk, Ilona, Kafarski, Paweł, Chmielewska, Ewa
Format: Artigo
Language:Inglês
Published: MDPI 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6155184/
https://ncbi.nlm.nih.gov/pubmed/28287472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules22030450
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