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Crystal structures of multicopper oxidase CueO G304K mutant: structural basis of the increased laccase activity
The multicopper oxidase CueO is involved in copper homeostasis and copper (Cu) tolerance in Escherichia coli. The laccase activity of CueO G304K mutant is higher than wild-type CueO. To explain this increase in activity, we solved the crystal structure of G304K mutant at 1.49 Å. Compared with wild-t...
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| הוצא לאור ב: | Sci Rep |
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| Main Authors: | , , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Nature Publishing Group UK
2018
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6155172/ https://ncbi.nlm.nih.gov/pubmed/30250139 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-32446-7 |
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