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SIRT1 suppresses the migration and invasion of gastric cancer by regulating ARHGAP5 expression

Gastric cancer (GC) ranks among the top five malignant tumors worldwide by the incidence and mortality rate. However, the mechanisms underlying its progression are poorly understood. In this study, we investigated the role of SIRT1, a class III deacetylase, in the invasion and metastasis of GC. Here...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Dong, Guoying, Wang, Bo, An, Yifei, Li, Juan, Wang, Xin, Jia, Jihui, Yang, Qing
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6155157/
https://ncbi.nlm.nih.gov/pubmed/30250020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-1033-8
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