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A naturally protective epitope of limited variability as an influenza vaccine target

Current antigenic targets for influenza vaccine development are either highly immunogenic epitopes of high variability or conserved epitopes of low immunogenicity. This requires continuous update of the variable epitopes in the vaccine formulation or boosting of immunity to invariant epitopes of low...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Thompson, Craig P., Lourenço, José, Walters, Adam A., Obolski, Uri, Edmans, Matthew, Palmer, Duncan S., Kooblall, Kreepa, Carnell, George W., O’Connor, Daniel, Bowden, Thomas A., Pybus, Oliver G., Pollard, Andrew J., Temperton, Nigel J., Lambe, Teresa, Gilbert, Sarah C., Gupta, Sunetra
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6155085/
https://ncbi.nlm.nih.gov/pubmed/30242149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06228-8
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