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A novel mechanism of SRRM4 in promoting neuroendocrine prostate cancer development via a pluripotency gene network
BACKGROUND: Prostate adenocarcinoma (AdPC) cells can undergo lineage switching to neuroendocrine cells and develop into therapy-resistant neuroendocrine prostate cancer (NEPC). While genomic/epigenetic alterations are shown to induce neuroendocrine differentiation via an intermediate stem-like state...
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| Veröffentlicht in: | EBioMedicine |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Elsevier
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6154886/ https://ncbi.nlm.nih.gov/pubmed/30100395 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2018.08.011 |
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