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Pro-Angiogenic Effects of Low Dose Ethoxidine in a Murine Model of Ischemic Hindlimb: Correlation between Ethoxidine Levels and Increased Activation of the Nitric Oxide Pathway

Ethoxidine, a benzo[c]phenanthridine derivative, has been identified as a potent inhibitor of topoisomerase I in cancer cell lines. Our group has reported paradoxical properties of ethoxidine in cellular processes leading to angiogenesis on endothelial cells. Because low concentration ethoxidine is...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Molecules
Hauptverfasser: Clere, Nicolas, To, Kim Hung Thien, Legeay, Samuel, Bertrand, Samuel, Helesbeux, Jean Jacques, Duval, Olivier, Faure, Sébastien
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6154657/
https://ncbi.nlm.nih.gov/pubmed/28417947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules22040627
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