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Fluoxetine Inhibits Canonical Wnt Signaling to Impair Embryoid Body Morphogenesis: Potential Teratogenic Mechanisms of a Commonly Used Antidepressant

Fluoxetine is one of the most commonly prescribed antidepressants in the selective serotonin reuptake inhibitor (SSRI) class. Epidemiologic studies have suggested a link between maternal fluoxetine use during pregnancy and an increased incidence of birth defects. However, the mechanisms by which flu...

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Publicat a:Toxicol Sci
Autors principals: Warkus, Erica L L, Marikawa, Yusuke
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2018
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6154268/
https://ncbi.nlm.nih.gov/pubmed/29893963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfy143
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