Development of a Multiplexed Activity-Based Protein Profiling Assay to Evaluate Activity of Endocannabinoid Hydrolase Inhibitors

[Image: see text] Endocannabinoids, an important class of signaling lipids involved in health and disease, are predominantly synthesized and metabolized by enzymes of the serine hydrolase superfamily. Activity-based protein profiling (ABPP) using fluorescent probes, such as fluorophosphonate (FP)-TA...

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Gepubliceerd in:ACS Chem Biol
Hoofdauteurs: Janssen, Antonius P. A., van der Vliet, Daan, Bakker, Alexander T., Jiang, Ming, Grimm, Sebastian H., Campiani, Giuseppe, Butini, Stefania, van der Stelt, Mario
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Chemical Society 2018
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6154214/
https://ncbi.nlm.nih.gov/pubmed/30199617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.8b00534
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