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Effect of Tadalafil on Seizure Threshold and Activity of Antiepileptic Drugs in Three Acute Seizure Tests in Mice

Tadalafil, a selective phosphodiesterase type 5 inhibitor, is a long-acting oral agent for the treatment of erectile dysfunction of multiple etiologies. Although generalized tonic-clonic seizures were reported in a healthy man after taking tadalafil, the influence of tadalafil on seizure susceptibil...

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Publicado en:Neurotox Res
Autores principales: Socała, Katarzyna, Nieoczym, Dorota, Pieróg, Mateusz, Wyska, Elżbieta, Szafarz, Małgorzata, Doboszewska, Urszula, Wlaź, Piotr
Formato: Artigo
Lenguaje:Inglês
Publicado: Springer US 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6154210/
https://ncbi.nlm.nih.gov/pubmed/29427285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12640-018-9876-4
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