Identification of an enhancer region within the TP63/LEPREL1 locus containing genetic variants associated with bladder cancer risk

PURPOSE: Genome-wide association studies (GWAS) have led to the identification of a bladder cancer susceptibility variant (rs710521) in a non-coding intergenic region between the TP63 and LEPREL1 genes on chromosome 3q28, suggesting a role in the transcriptional regulation of these genes. In this st...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Oncol (Dordr)
Prif Awduron: Dudek, Aleksandra M., Vermeulen, Sita H., Kolev, Dimitar, Grotenhuis, Anne J., Kiemeney, Lambertus A. L. M., Verhaegh, Gerald W.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Springer Netherlands 2018
Pynciau:
Original Paper
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6153957/
https://ncbi.nlm.nih.gov/pubmed/29956121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13402-018-0393-5
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