Na(+)(i),K(+)(i)-Dependent and -Independent Signaling Triggered by Cardiotonic Steroids: Facts and Artifacts

Na(+),K(+)-ATPase is the only known receptor of cardiotonic steroids (CTS) whose interaction with catalytic α-subunits leads to inhibition of this enzyme. As predicted, CTS affect numerous cellular functions related to the maintenance of the transmembrane gradient of monovalent cations, such as elec...

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Bibliographic Details
Published in:Molecules
Main Authors: Orlov, Sergei N., Klimanova, Elizaveta A., Tverskoi, Artem M., Vladychenskaya, Elizaveta A., Smolyaninova, Larisa V., Lopina, Olga D.
Format: Artigo
Language:Inglês
Published: MDPI 2017
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6153942/
https://ncbi.nlm.nih.gov/pubmed/28420099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules22040635
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