Characterization of Mutations Conferring Resistance to Rifampin in Mycobacterium tuberculosis Clinical Strains

Resistance of Mycobacterium tuberculosis to rifampin (RMP), mediated by mutations in the rpoB gene coding for the beta-subunit of RNA polymerase, poses a serious threat to the efficacy of clinical management and, thus, control programs for tuberculosis (TB). The contribution of many individual rpoB...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Jagielski, Tomasz, Bakuła, Zofia, Brzostek, Anna, Minias, Alina, Stachowiak, Radosław, Kalita, Joanna, Napiórkowska, Agnieszka, Augustynowicz-Kopeć, Ewa, Żaczek, Anna, Vasiliauskiene, Edita, Bielecki, Jacek, Dziadek, Jarosław
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Mechanisms of Resistance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6153850/
https://ncbi.nlm.nih.gov/pubmed/30061294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01093-18
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