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Lysostaphin Lysibody Leads to Effective Opsonization and Killing of Methicillin-Resistant Staphylococcus aureus in a Murine Model

The cell wall of Gram-positive bacteria contains abundant surface-exposed carbohydrate structures that are highly conserved. While these properties make surface carbohydrates ideal targets for immunotherapy, carbohydrates elicit a poor immune response that results primarily in low-affinity IgM antib...

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Dettagli Bibliografici
Pubblicato in:Antimicrob Agents Chemother
Autori principali: Raz, Assaf, Serrano, Anna, Thaker, Maneesha, Alston, Tricia, Fischetti, Vincent A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6153821/
https://ncbi.nlm.nih.gov/pubmed/30038041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01056-18
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