Population Pharmacokinetics of Artemether, Dihydroartemisinin, and Lumefantrine in Rwandese Pregnant Women Treated for Uncomplicated Plasmodium falciparum Malaria

The artemisinin-based combination therapy artemether-lumefantrine is commonly used in pregnant malaria patients. However, the effect of pregnancy-related changes on exposure is unclear, and pregnancy has been associated with decreased efficacy in previous studies. This study aimed to characterize th...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Lohy Das, Jesmin, Rulisa, Stephen, de Vries, Peter J., Mens, Petra F., Kaligirwa, Nadine, Agaba, Steven, Tarning, Joel, Karlsson, Mats O., Dorlo, Thomas P. C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6153812/
https://ncbi.nlm.nih.gov/pubmed/30061282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00518-18
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