Local Skin Inflammation in Cutaneous Leishmaniasis as a Source of Variable Pharmacokinetics and Therapeutic Efficacy of Liposomal Amphotericin B

Disfiguring skin lesions caused by several species of the Leishmania parasite characterize cutaneous leishmaniasis (CL). Successful treatment of CL with intravenous (i.v.) liposomal amphotericin B (LAmB) relies on the presence of adequate antibiotic concentrations at the dermal site of infection wit...

Full description

Saved in:
Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: Wijnant, Gert-Jan, Van Bocxlaer, Katrien, Fortes Francisco, Amanda, Yardley, Vanessa, Harris, Andy, Alavijeh, Mo, Murdan, Sudaxshina, Croft, Simon L.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2018
Subjects:
Pharmacology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6153808/
https://ncbi.nlm.nih.gov/pubmed/30082295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00631-18
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items